The first head-to-head test of two popular weight-loss drugs has a clear winner, a new study suggests. It compares the results of those taking tirzepatide, known as Mounjaro and Zepbound, and those using semaglutide, known as Ozempic and Wegovy, and finds that people using Mounjaro and Zepbound tend to shed more pounds.
According to the study, both drugs led to substantial weight loss, but those using Mounjaro and Zepbound lost around 20% of their body weight after 72 weeks on the drug, while those taking Wegovy and Ozempic dropped around 14%. "That translates to about a difference of eight pounds on average between the two drugs," explains Dr. Céline Gounder, CBS News medical contributor. She also points out that the study was funded by Lilly, who makes tirzepatide, noting, “So you always need to take that with a grain of salt,” even though the research “does look legit.”
Both of the drugs work by tricking the brain into making you feel full, so you eat less and burn fat instead, but they are slightly different. Semaglutide mimics a hormone the body releases after a meal to flip one appetite switch in the brain, while tirzepatide flips two switches. Dr. Gounder explains that in addition to weight loss, the drugs come with extra health benefits, including lower blood pressure and better blood sugar and cholesterol numbers.
Source: CBS News
Scott's Thoughts:
- Proof that everyone really is taking these weight loss drugs? Weight Watchers has filed for bankruptcy!
- I use them. Not ashamed. Of course I am diabetic. Not just fat.
- If you could get a jab of a drug to help with something other than weight loss, what would you want it to do? I’d try one that promised to help with sleep!