Coming off weight-loss drugs like Ozempic? Just know the pounds don’t stay gone forever. A review of 11 clinical trials found that most people start regaining weight around eight weeks after stopping and typically plateau after about 20 weeks. Whether it’s semaglutide (Ozempic/Wegovy), tirzepatide (Mounjaro), or liraglutide (Saxenda), the common thread is that results fade fast without ongoing support. It’s a reminder that maintaining healthy habits is just as crucial as the meds themselves.
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